Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 11/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404027 | 0.95 | F10 (0.41) | F10CTSKF2F11PRSS1 | |
| SCHEMBL7950828 | 0.79 | ALDH1A1 (0.42) | F10CTSKF2F11 | |
| SCHEMBL23862150 | 0.76 | F11 (0.40) | F10CTSKF2F11 | |
| SCHEMBL8800894 | 0.76 | ALDH1A1 (0.44) | F10CTSKF2 | |
| SCHEMBL19933184 | 0.75 | NPY4R (0.47) | F10F2F11 | |
| SCHEMBL23752319 | 0.75 | F11 (0.44) | F10CTSKF2F11PRSS1 | |
| SCHEMBL19630898 | 0.74 | F2 (0.48) | F10CTSKF2F11PRSS1 | |
| SCHEMBL8797816 | 0.74 | SMYD3 (0.38) | — | |
| SCHEMBL24131682 | 0.73 | F10 (0.41) | F10CTSKF2F11PRSS1 | |
| SCHEMBL22851075 | 0.73 | NPY4R (0.44) | F10F2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802916-A1 | LOW MOLECULAR WEIGHT BICYCLIC THROMBIN INHIBITORS | BIOCHEM PHARMA INC (CA) | 1997-10-29 | — | — | EP | disclosed |