Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.69 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801114 | 0.93 | CTSD (0.66) | CTSDCCR1RENOPRM1OPRK1 | |
| SCHEMBL8800871 | 0.90 | CTSD (0.86) | CTSDCCR1RENOPRM1OPRK1 | |
| SCHEMBL7299644 | 0.90 | CTSD (0.62) | CTSDCCR1OPRM1OPRK1TMEM97 | |
| SCHEMBL8800567 | 0.88 | CTSD (0.61) | CTSDCCR1RENHDAC1ALDH1A1 | |
| SCHEMBL8800743 | 0.87 | CTSD (0.59) | CTSDCCR1RENHDAC1PSMB5 | |
| SCHEMBL8801929 | 0.83 | CTSD (0.82) | CTSDCCR1RENOPRM1OPRK1 | |
| SCHEMBL7313674 | 0.83 | CTSD (0.80) | CTSDCCR1RENOPRM1OPRK1 | |
| SCHEMBL8800938 | 0.80 | CTSD (0.74) | CTSDRENOPRM1OPRK1HDAC1 | |
| SCHEMBL8800288 | 0.79 | CTSD (0.73) | CTSDCCR1RENOPRM1OPRK1 | |
| SCHEMBL8801937 | 0.79 | CTSD (0.78) | CTSDCCR1RENOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601486-B1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD (KR) | 1997-10-29 | — | — | EP | claimed |