Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 6/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800288 | 0.92 | CTSD (0.73) | CTSDHDAC1KMT2ACCR1ALDH1A1 | |
| SCHEMBL8801074 | 0.87 | CTSD (0.69) | CTSDHDAC1CCR1ALDH1A1MAPT | |
| SCHEMBL8801485 | 0.87 | CTSD (0.68) | CTSDHDAC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8800567 | 0.86 | CTSD (0.61) | CTSDHDAC1KMT2ACCR1ALDH1A1 | |
| SCHEMBL8801114 | 0.85 | CTSD (0.66) | CTSDHDAC1CCR1ALDH1A1REN | |
| SCHEMBL7299644 | 0.82 | CTSD (0.62) | CTSDHDAC1CCR1ALDH1A1MAPT | |
| SCHEMBL8800938 | 0.79 | CTSD (0.74) | CTSDHDAC1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8800871 | 0.78 | CTSD (0.86) | CTSDHDAC1CCR1ALDH1A1CYP3A4 | |
| SCHEMBL8802750 | 0.77 | CTSD (0.76) | CTSDHDAC1CCR1ALDH1A1CYP3A4 | |
| SCHEMBL8801929 | 0.76 | CTSD (0.82) | CTSDHDAC1CCR1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601486-B1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD (KR) | 1997-10-29 | — | — | EP | claimed |
| EP-0601486-A1 | Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation | LUCKY LTD. (KR) | 1994-06-15 | — | — | EP | claimed |