Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 9/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408849 | 0.88 | DCTPP1 (0.40) | CA2CA1LPLLIPGTRPV1 | |
| SCHEMBL8801753 | 0.87 | CA1 (0.40) | CA2CA1LPLLIPGTRPV1 | |
| SCHEMBL8802291 | 0.84 | THRB (0.34) | CA2CA1KDM4EMEN1ALDH1A1 | |
| SCHEMBL7418136 | 0.83 | KMT2A (0.43) | CA2CA1LPLLIPGTRPV1 | |
| SCHEMBL7413514 | 0.79 | CA1 (0.40) | CA2CA1LPLLIPGTRPV1 | |
| SCHEMBL7408857 | 0.78 | CA1 (0.43) | CA2CA1LPLLIPGTRPV1 | |
| SCHEMBL7413574 | 0.76 | KDM4E (0.43) | CA2CA1LPLLIPGTRPV1 | |
| SCHEMBL8801490 | 0.75 | PSEN1 (0.42) | CA2CA1LPLLIPGTRPV1 | |
| SCHEMBL8802098 | 0.75 | CA1 (0.40) | CA2CA1LPLLIPGTRPV1 | |
| SCHEMBL8802217 | 0.75 | LPL (0.44) | CA2CA1LPLLIPGTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640080-B1 | SUBSTITUTED INDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX INC (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5380739-A | Angiotensin II antagonists | SYNTEX (U.S.A.) INC. (US) | 1995-01-10 | — | — | US | disclosed |