Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3906596 | 0.80 | SLC5A2 (0.52) | TRPA1SLC5A2CES2CES1KEAP1 | |
| SCHEMBL8801566 | 0.80 | SLC6A2 (0.48) | TRPA1HPGDTAAR1SLC6A2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8800673 | 0.79 | SLC6A2 (0.47) | TRPA1HPGDTAAR1SLC6A2SIGMAR1 | |
| SCHEMBL8800678 | 0.78 | TSHR (0.42) | HPGDTAAR1SLC6A2SIGMAR1MAOA | |
| SCHEMBL5179686 | 0.77 | ALOX5 (0.44) | HPGDCES2CES1KEAP1KMT2A | |
| SCHEMBL8800929 | 0.75 | TSHR (0.41) | HPGDTAAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL8801053 | 0.74 | TDP1 (0.38) | SLC5A2HPGDTAAR1SLC6A2SIGMAR1 | |
| SCHEMBL24925796 | 0.74 | ALOX5 (0.46) | HPGDSLC6A2SLC6A4SLC6A3CES2 | |
| SCHEMBL27887249 | 0.74 | ALOX5 (0.46) | HPGDSLC6A2SLC6A4SLC6A3CES2 | |
| SCHEMBL7362430 | 0.73 | TAAR1 (0.40) | TRPA1HPGDTAAR1SLC6A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |