Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8800673 | 0.98 | SLC6A2 (0.47) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL6650848 | 0.80 | EPHX1 (0.42) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL8801211 | 0.80 | TRPA1 (0.46) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL30846613 | 0.79 | EPHX1 (0.48) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL3289195 | 0.79 | EPHX1 (0.48) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL30846601 | 0.79 | EPHX1 (0.48) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL8800678 | 0.78 | TSHR (0.42) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9482622 | 0.77 | EPHX1 (0.47) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL4692960 | 0.76 | TAAR1 (0.67) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL7286460 | 0.76 | TAAR1 (0.67) | SLC6A2TAAR1MAOASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |