Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801053 | 0.81 | TDP1 (0.38) | TSHRALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8801211 | 0.75 | TRPA1 (0.46) | TSHRKMT2AMEN1HPGDNPC1 | |
| SCHEMBL8801566 | 0.75 | SLC6A2 (0.48) | TSHRHPGDMAOASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL8800673 | 0.74 | SLC6A2 (0.47) | TSHRHPGDMAOASLC6A2SLC6A4 | |
| SCHEMBL8800678 | 0.73 | TSHR (0.42) | TSHRALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8802018 | 0.71 | LMNA (0.38) | TSHRALDH1A1KMT2AMEN1HTT | |
| SCHEMBL3615431 | 0.70 | GAA (0.41) | TSHRALDH1A1KMT2AHTTLMNA | |
| SCHEMBL7362430 | 0.69 | TAAR1 (0.40) | HPGDLMNAMAOASLC6A2SLC6A4 | |
| SCHEMBL9366025 | 0.69 | TSHR (0.62) | TSHRALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8800512 | 0.69 | HPGD (0.36) | TSHRALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |