Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801591 | 0.83 | ALOX5 (0.62) | ALOX5HDAC6 | |
| SCHEMBL8801751 | 0.83 | ALOX5 (0.62) | ALOX5HDAC6 | |
| SCHEMBL8801764 | 0.82 | ALOX5 (0.62) | ALOX5HDAC6 | |
| SCHEMBL8800980 | 0.81 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL8803948 | 0.78 | ALOX5 (0.58) | ALOX5PDE10AHDAC6 | |
| SCHEMBL8801122 | 0.76 | ALOX5 (0.60) | ALOX5 | |
| SCHEMBL8799938 | 0.74 | ALOX5 (0.62) | ALOX5HDAC6 | |
| SCHEMBL8965337 | 0.73 | ALOX5 (0.61) | ALOX5PDE10AHDAC6 | |
| SCHEMBL9428765 | 0.72 | ALOX5 (0.49) | ALOX5PDE10A | |
| SCHEMBL9472475 | 0.68 | ALOX5 (0.58) | ALOX5PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772594-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002507-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1996-02-01 | — | — | WO | disclosed |