Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9472475 | 0.91 | ALOX5 (0.58) | ALOX5PDE10A | |
| SCHEMBL9428888 | 0.85 | PDE10A (0.45) | ALOX5PDE10A | |
| SCHEMBL9427391 | 0.82 | ALOX5 (0.48) | ALOX5PDE10A | |
| SCHEMBL9428008 | 0.78 | NPC1 (0.53) | ALOX5 | |
| SCHEMBL9427508 | 0.77 | RAB9A (0.56) | ALOX5PDE10A | |
| SCHEMBL7713248 | 0.74 | ALOX5 (0.78) | ALOX5 | |
| SCHEMBL9591203 | 0.74 | AKR1C3 (0.56) | ALOX5PDE10A | |
| SCHEMBL7547340 | 0.74 | MEN1 (0.60) | PDE10A | |
| SCHEMBL9427979 | 0.73 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL8801273 | 0.72 | ALOX5 (0.59) | ALOX5PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218124-A | Antiinflammatory agents, antiallergens and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-08 | — | — | US | claimed |
| US-5364944-A | Antiinflammatory, antiallergic and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-15 | — | — | US | disclosed |
| US-5218124-A | Antiinflammatory agents, antiallergens and cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |