Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8137930 | 0.91 | MAOB (0.65) | CYSLTR1GPBAR1ALOX5MAOAMAOB | |
| SCHEMBL8801610 | 0.84 | MAOA (0.56) | CYSLTR1GPBAR1ALOX5MAOAMAOB | |
| SCHEMBL8800863 | 0.83 | MAOB (0.67) | CYSLTR1MAOAMAOBCYSLTR2 | |
| SCHEMBL8801120 | 0.82 | CYSLTR1 (0.51) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8144811 | 0.81 | MAOB (0.62) | CYSLTR1GPBAR1MAOAMAOBCYSLTR2 | |
| SCHEMBL8140431 | 0.80 | CYSLTR1 (0.53) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8139911 | 0.79 | MAOA (0.51) | CYSLTR1GPBAR1ALOX5MAOAMAOB | |
| SCHEMBL8802992 | 0.77 | CYSLTR1 (0.54) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8801669 | 0.77 | CYSLTR1 (0.54) | CYSLTR1GPBAR1ALOX5CYSLTR2 | |
| SCHEMBL8131552 | 0.77 | ALOX5 (0.50) | CYSLTR1GPBAR1ALOX5MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799826-A1 | Heteroaryl substituted phenylene derivatives, their preparation and their use as leukotriene receptor antagonists | KOWA CO. LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |