Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.51 |
| ▸ | REN | P00797 | 7/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8800018 | 0.99 | ALOX5 (0.50) | ALOX5RENHDAC6CACNA1BLTA4H | |
| SCHEMBL8800396 | 0.85 | ALOX5 (0.58) | ALOX5HDAC6 | |
| SCHEMBL8801740 | 0.81 | ALOX5 (0.61) | ALOX5HDAC6 | |
| SCHEMBL8799902 | 0.78 | ALOX5 (0.53) | ALOX5RENHDAC6CACNA1BLTA4H | |
| SCHEMBL8965181 | 0.77 | ALOX5 (0.51) | ALOX5RENHDAC6CACNA1BFFAR1 | |
| Hydroxyamine SCHEMBL8801279 | 0.76 | ALOX5 (0.43) | ALOX5RENLTA4H | |
| SCHEMBL8965166 | 0.76 | ALOX5 (0.49) | ALOX5RENHDAC6CACNA1BFFAR1 | |
| SCHEMBL8799338 | 0.73 | ALOX5 (0.52) | ALOX5CACNA1B | |
| SCHEMBL8966886 | 0.73 | ALOX5 (0.53) | ALOX5RENCACNA1BFFAR1 | |
| SCHEMBL8965350 | 0.71 | ALOX5 (0.53) | ALOX5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772594-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | Abbott Laboratories (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996002507-A1 | IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1996-02-01 | — | — | WO | disclosed |