Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965166 | 0.99 | ALOX5 (0.49) | ALOX5FFAR1HDAC6MMP13MMP14 | |
| SCHEMBL8965348 | 0.85 | ALOX5 (0.57) | ALOX5HDAC6 | |
| SCHEMBL8965428 | 0.84 | ALOX5 (0.55) | ALOX5HDAC6MMP13MMP14 | |
| SCHEMBL8964989 | 0.81 | ALOX5 (0.61) | ALOX5HDAC6 | |
| SCHEMBL8799902 | 0.78 | ALOX5 (0.53) | ALOX5HDAC6MMP13MMP14REN | |
| SCHEMBL8801528 | 0.77 | ALOX5 (0.51) | ALOX5FFAR1HDAC6RENCACNA1B | |
| SCHEMBL8800018 | 0.76 | ALOX5 (0.50) | ALOX5HDAC6MMP13MMP14REN | |
| SCHEMBL8799338 | 0.72 | ALOX5 (0.52) | ALOX5MMP13MMP14CACNA1B | |
| SCHEMBL8966886 | 0.72 | ALOX5 (0.53) | ALOX5FFAR1RENCACNA1B | |
| SCHEMBL8800396 | 0.70 | ALOX5 (0.58) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512581-A | ANTIINFLAMMATORY AGENT | ABBOTT LABORATORIES (US) | 1996-04-30 | — | — | US | disclosed |