Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 16/20 | 0.37 |
| ▸ | EIF2S1 | P05198 | 15/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL880168 | 1.00 | EIF2AK3 (0.37) | EIF2AK3EIF2S1CES2CES1PSEN1 | |
| SCHEMBL29815125 | 1.00 | EIF2AK3 (0.37) | EIF2AK3EIF2S1CES2CES1PSEN1 | |
| SCHEMBL6518734 | 1.00 | EIF2AK3 (0.37) | EIF2AK3EIF2S1CES2CES1PSEN1 | |
| SCHEMBL1841636 | 0.87 | CES2 (0.38) | CES2CES1 | |
| SCHEMBL6520061 | 0.86 | EIF2S1 (0.39) | EIF2AK3EIF2S1 | |
| SCHEMBL29254400 | 0.85 | ALDH1A1 (0.41) | — | |
| SCHEMBL880174 | 0.82 | EIF2S1 (0.37) | EIF2AK3EIF2S1PSEN1PSEN2APH1B | |
| SCHEMBL880173 | 0.82 | EIF2S1 (0.37) | EIF2AK3EIF2S1PSEN1PSEN2APH1B | |
| SCHEMBL6518890 | 0.81 | MAPT (0.43) | — | |
| SCHEMBL880178 | 0.81 | MAPT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118303403-A | Application of EMD 638683R-Form in improving plant disease resistance | 湖南大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118303403-A | Application of EMD 638683R-Form in improving plant disease resistance | 湖南大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-118303403-A | Application of EMD 638683R-Form in improving plant disease resistance | 湖南大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-118303403-A | Application of EMD 638683R-Form in improving plant disease resistance | 湖南大学 | 2024-07-09 | — | — | CN | disclosed |
| US-8546613-B2 | SGK1 inhibitors for the prophylaxis and/or therapy of viral diseases and/or carcinomas | MERCK PATENT GMBH (DE) | 2013-10-01 | — | — | US | disclosed |
| US-8546613-B2 | SGK1 inhibitors for the prophylaxis and/or therapy of viral diseases and/or carcinomas | MERCK PATENT GMBH (DE) | 2013-10-01 | — | — | US | disclosed |
| EP-2242738-B1 | SGK1 INHIBITORS FOR THE PROPHYLAXIS AND/OR THERAPY OF VIRAL DISEASES AND/OR CARCINOMAS | MERCK PATENT GMBH (DE) | 2012-03-28 | — | — | EP | disclosed |
| US-20110060050-A1 | SGK1 INHIBITORS FOR THE PROPHYLAXIS AND/OR THERAPY OF VIRAL DISEASES AND/OR CARCINOMAS | MERCK PATENT GMBH (DE) | 2011-03-10 | — | — | US | disclosed |
| US-20110060050-A1 | SGK1 INHIBITORS FOR THE PROPHYLAXIS AND/OR THERAPY OF VIRAL DISEASES AND/OR CARCINOMAS | MERCK PATENT GMBH (DE) | 2011-03-10 | — | — | US | disclosed |
| WO-2009103484-A1 | SGK1 INHIBITORS FOR THE PROPHYLAXIS AND/OR THERAPY OF VIRAL DISEASES AND/OR CARCINOMAS | MERCK PATENT GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060050-A1 | SGK1 INHIBITORS FOR THE PROPHYLAXIS AND/OR THERAPY OF VIRAL DISEASES AND/OR CARCINOMAS | NCOA1, NR3C2, NCOA2 | EIF2AK3 453/4885EIF2S1 927/4885CES2 2171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.