Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803077 | 0.81 | IDO1 (0.49) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL4979608 | 0.77 | SIGMAR1 (0.55) | IDO1EP300KAT8SCN2A | |
| SCHEMBL8801835 | 0.72 | PLK1 (0.49) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL9117418 | 0.71 | SCN2A (0.45) | IDO1EP300KAT8PLK1ALDH1A1 | |
| SCHEMBL29380721 | 0.71 | IDO1 (0.73) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL419307 | 0.71 | IDO1 (0.73) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL4981353 | 0.70 | SIGMAR1 (0.44) | IDO1EP300KAT8SCN2A | |
| SCHEMBL8334176 | 0.70 | IDO1 (0.38) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL9162210 | 0.69 | IDO1 (0.50) | IDO1EP300KAT8IMPDH2IMPDH1 | |
| SCHEMBL4984086 | 0.69 | SIGMAR1 (0.56) | IDO1EP300KAT8IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751767-A4 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE INC (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0751767-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1997-01-08 | — | — | EP | disclosed |