Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801859 | 0.88 | LMNA (0.46) | CYP19A1IDO1TDO2LMNAMEN1 | |
| SCHEMBL8801932 | 0.87 | LMNA (0.46) | LMNAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8803908 | 0.87 | ALDH1A1 (0.40) | CYP19A1IDO1TDO2KDM4EALDH1A1 | |
| SCHEMBL8804235 | 0.87 | LMNA (0.51) | IDO1TDO2LMNAMEN1KMT2A | |
| SCHEMBL8801266 | 0.87 | LMNA (0.46) | IDO1TDO2LMNAMEN1KMT2A | |
| SCHEMBL8802521 | 0.87 | GRM2 (0.34) | CYP19A1IDO1TDO2LMNAMEN1 | |
| SCHEMBL8804845 | 0.87 | PDE4A (0.34) | CYP19A1IDO1TDO2LMNAMEN1 | |
| SCHEMBL8801570 | 0.86 | PIM1 (0.37) | CYP19A1IDO1TDO2MAPK8KDM4E | |
| SCHEMBL8801295 | 0.83 | CYP11B1 (0.43) | CYP19A1LMNAMEN1KMT2A | |
| SCHEMBL8801661 | 0.81 | LMNA (0.41) | LMNAMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612731-B1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1997-08-20 | — | — | EP | disclosed |
| EP-0612731-A1 | Novel guinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-08-31 | — | — | EP | disclosed |