Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.49 |
| ▸ | KDM1A | O60341 | 6/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4938913 | 0.81 | KDM1A (0.51) | KDM1AHDAC1HDAC6HDAC2HDAC11 | |
| SCHEMBL29445848 | 0.81 | KMO (0.54) | KMOKDM1AMEN1KMT2AFAAH | |
| SCHEMBL19072696 | 0.81 | KMO (0.54) | KMOKDM1AMEN1KMT2AFAAH | |
| SCHEMBL8802396 | 0.80 | KMO (0.46) | KMOKDM1AHDAC1HDAC6HDAC2 | |
| SCHEMBL9939619 | 0.78 | MEN1 (0.44) | KDM1AHDAC1HDAC6HDAC5MEN1 | |
| SCHEMBL9607471 | 0.77 | ALDH1A1 (0.45) | KMOHDAC1HDAC6HDAC2HDAC11 | |
| SCHEMBL14879562 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1POLBHPGD | |
| SCHEMBL730405 | 0.76 | CCR1 (0.42) | ALDH1A1KDM4AKDM4CRAB9A | |
| SCHEMBL29387096 | 0.76 | CCR1 (0.42) | ALDH1A1KDM4AKDM4CRAB9A | |
| SCHEMBL19847066 | 0.76 | KDM1A (0.40) | KDM1AHDAC1HDAC6HDAC2HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695751-B1 | AGENT ACTING ON THE CENTRAL NERVOUS SYSTEM, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | VITA INVEST SA (ES) | 1997-03-26 | — | — | EP | disclosed |
| EP-0695751-A1 | AGENT ACTING ON THE CENTRAL NERVOUS SYSTEM, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | VITA-INVEST, S.A. (ES) | 1996-02-07 | — | — | EP | disclosed |