Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | ADK | P55263 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.36 |
| ▸ | TUBB | P07437 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057701 | 0.84 | HTT (0.49) | SLC22A6KIF11HTTMAPTKDM4E | |
| SCHEMBL8803144 | 0.81 | SLC22A6 (0.41) | SLC22A6HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL8801465 | 0.79 | SLC22A6 (0.40) | SLC22A6HTTMAPTKDM4EALDH1A1 | |
| SCHEMBL8390401 | 0.78 | MAPT (0.41) | KIF11MCL1MAPTKDM4EALDH1A1 | |
| SCHEMBL8801909 | 0.76 | SLC22A6 (0.48) | SLC22A6KIF11HTTMAPTKDM4E | |
| SCHEMBL8388289 | 0.73 | SLC22A6 (0.48) | SLC22A6KIF11HTTMAPTKDM4E | |
| SCHEMBL9056901 | 0.70 | MEN1 (0.42) | MCL1MAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL9056902 | 0.70 | MEN1 (0.42) | MCL1MAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL9055605 | 0.69 | KDM4E (0.35) | MAPTKDM4EALDH1A1MAPK1HSD17B10 | |
| SCHEMBL9055602 | 0.68 | GABRP (0.35) | MAPTKDM4EALDH1A1HSD17B10TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |