Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ADK | P55263 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.36 |
| ▸ | TUBB | P07437 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803144 | 0.85 | SLC22A6 (0.41) | HTTMAPTMEN1KMT2ASLC22A6 | |
| SCHEMBL8802131 | 0.84 | SLC22A6 (0.40) | HTTMAPTMEN1KMT2ASLC22A6 | |
| SCHEMBL8801465 | 0.83 | SLC22A6 (0.40) | HTTMAPTSLC22A6GSK3BADK | |
| SCHEMBL8801909 | 0.80 | SLC22A6 (0.48) | HTTMAPTMEN1KMT2ASLC22A6 | |
| SCHEMBL8388289 | 0.77 | SLC22A6 (0.48) | HTTMAPTMEN1KMT2ASLC22A6 | |
| SCHEMBL8390363 | 0.76 | MAPT (0.47) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL9056823 | 0.72 | KDM4E (0.46) | HTTMAPTMEN1KMT2ASLC22A6 | |
| SCHEMBL9055605 | 0.72 | KDM4E (0.35) | MAPTKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL9055602 | 0.71 | GABRP (0.35) | MAPTMEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL21479880 | 0.71 | GSK3B (0.49) | HTTMAPTMEN1KMT2ASLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |