Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | ADK | P55263 | 2/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056775 | 0.87 | PARP14 (0.40) | SLC22A6PARP14HTTMPLPIM3 | |
| SCHEMBL9056003 | 0.82 | SLC22A6 (0.51) | SLC22A6GSK3BADKPARP14HTT | |
| SCHEMBL8388289 | 0.81 | SLC22A6 (0.48) | SLC22A6GSK3BADKHTTKIF11 | |
| SCHEMBL8391232 | 0.81 | MAPT (0.48) | MPLMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4786156 | 0.80 | SLC22A6 (0.55) | SLC22A6GSK3BADKPARP14HTT | |
| SCHEMBL9057701 | 0.80 | HTT (0.49) | SLC22A6GSK3BADKHTTKIF11 | |
| SCHEMBL8803144 | 0.77 | SLC22A6 (0.41) | SLC22A6GSK3BADKHTTMAPT | |
| SCHEMBL8802131 | 0.76 | SLC22A6 (0.40) | SLC22A6GSK3BADKHTTKIF11 | |
| SCHEMBL8801465 | 0.75 | SLC22A6 (0.40) | SLC22A6GSK3BADKHTTMAPT | |
| SCHEMBL8387263 | 0.75 | KIF11 (0.47) | PARP14MPLPIM3PIM1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |