Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 18/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 17/20 | 0.46 |
| ▸ | TSPO | P30536 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801888 | 0.88 | LTB4R (0.53) | LTB4RLTB4R2 | |
| SCHEMBL8802549 | 0.76 | LTB4R (0.60) | LTB4RLTB4R2 | |
| SCHEMBL8802166 | 0.75 | LTB4R (0.55) | LTB4RLTB4R2 | |
| SCHEMBL8801953 | 0.74 | LTB4R (0.53) | LTB4RLTB4R2 | |
| SCHEMBL9023405 | 0.74 | LTB4R (0.59) | LTB4RLTB4R2TSPO | |
| SCHEMBL8801777 | 0.73 | LTB4R (0.56) | LTB4RLTB4R2 | |
| SCHEMBL8801516 | 0.71 | LTB4R (0.50) | LTB4RLTB4R2 | |
| SCHEMBL8477735 | 0.70 | LTB4R (0.61) | LTB4RLTB4R2 | |
| SCHEMBL8803323 | 0.69 | LTB4R (0.59) | LTB4RLTB4R2 | |
| SCHEMBL8801356 | 0.68 | LTB4R (0.40) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805810-A1 | NOVEL 9H-PYRIDO 3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022989-A1 | NOVEL 9H-PYRIDO[3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-01 | — | — | WO | disclosed |