Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 19/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 17/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802166 | 0.89 | LTB4R (0.55) | LTB4RLTB4R2GABRPGABRDGABRA1 | |
| SCHEMBL8802375 | 0.88 | LTB4R (0.46) | LTB4RLTB4R2 | |
| SCHEMBL8801953 | 0.87 | LTB4R (0.53) | LTB4RLTB4R2GABRPGABRDGABRA1 | |
| SCHEMBL8801516 | 0.84 | LTB4R (0.50) | LTB4RLTB4R2GABRPGABRDGABRA1 | |
| SCHEMBL8801942 | 0.79 | TSPO (0.45) | LTB4RLTB4R2GABRPGABRDGABRA1 | |
| SCHEMBL8802594 | 0.77 | LTB4R (0.42) | LTB4RLTB4R2GABRPGABRDGABRA1 | |
| SCHEMBL8806843 | 0.76 | LTB4R (0.52) | LTB4RLTB4R2 | |
| SCHEMBL8801356 | 0.74 | LTB4R (0.40) | LTB4RLTB4R2 | |
| SCHEMBL9023753 | 0.74 | LTB4R (0.69) | LTB4RLTB4R2 | |
| SCHEMBL9023751 | 0.74 | LTB4R (0.69) | LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805810-A1 | NOVEL 9H-PYRIDO 3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022989-A1 | NOVEL 9H-PYRIDO[3,4-B]INDOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-08-01 | — | — | WO | disclosed |