Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL880460 | 0.85 | KMT2A (0.64) | TP53ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL10280290 | 0.83 | LMNA (0.70) | TP53ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL880459 | 0.80 | SMN1; SMN2 (0.66) | TP53ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL14942698 | 0.78 | LMNA (0.55) | TP53ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL880458 | 0.77 | KMT2A (0.68) | TP53ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL10280347 | 0.74 | KMT2A (0.70) | TP53ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL880218 | 0.73 | ALDH1A1 (0.61) | TP53ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL880359 | 0.72 | TP53 (0.71) | TP53ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL15427001 | 0.72 | MAPT (0.72) | TP53ALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL880464 | 0.70 | TP53 (0.76) | TP53ALDH1A1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433634-A2 | Compounds, compositions and methods of inhibiting a-synuclein toxicity | The Whitehead Institute for Biomedical Research (US) | 2012-03-28 | — | — | EP | disclosed |