Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807301 | 0.81 | KDM4E (0.44) | CCR1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL8806761 | 0.78 | CCR1 (0.43) | CCR1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL9719915 | 0.77 | CCR1 (0.48) | CCR1MAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL8806831 | 0.77 | THRB (0.39) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8805283 | 0.76 | THRB (0.39) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL29061980 | 0.74 | PTGS2 (0.47) | CCR1MAPTMAPK1TUBB4ATUBB | |
| SCHEMBL10910082 | 0.74 | PTGS2 (0.47) | CCR1MAPTMAPK1TUBB4ATUBB | |
| SCHEMBL9491753 | 0.71 | KMT2A (0.39) | CCR1KMT2AMAPK1SMN1; SMN2TUBB4A | |
| SCHEMBL7265584 | 0.70 | CCR1 (0.42) | CCR1MEN1KMT2AMAPK1CYP3A4 | |
| SCHEMBL11647498 | 0.69 | ACHE (0.44) | MAPTMEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633288-A | EXPECTORANT | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0555481-B1 | TRI(C1-C6 ALKOXY)BENZENE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5498635-A | RESPIRATORY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| US-5401775-A | Pulmonary surfactant secretion promoter | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0555481-A1 | TRI(C1-C6 ALKOXY)BENZENE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |