Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8673420 | 0.95 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL8667909 | 0.91 | ACHE (0.49) | AGTR1AGTR2 | |
| SCHEMBL9203184 | 0.90 | AGTR2 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8802893 | 0.86 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL8668466 | 0.85 | ACHE (0.44) | AGTR1AGTR2 | |
| SCHEMBL9202522 | 0.84 | ACHE (0.41) | AGTR1AGTR2 | |
| SCHEMBL8672202 | 0.83 | SLC33A1 (0.38) | — | |
| SCHEMBL8669886 | 0.82 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL8671503 | 0.82 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL8801166 | 0.80 | AGTR1 (0.48) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680480-B1 | PYRIMIDINONE DERIVATIVES FUSED TO NITROGEN HETEROCYCLES HAVING A II ANTAGONISTIC ACTIVITY | LUSO FARMACO INST (IT) | 1997-07-30 | — | — | EP | disclosed |
| WO-1994017067-A1 | PYRIMIDINONE DERIVATIVES FUSED TO NITROGEN HETEROCYCLES HAVING A II ANTAGONISTIC ACTIVITY | ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) | 1994-08-04 | — | — | WO | disclosed |