Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 4/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805075 | 0.84 | TRPV1 (0.36) | F2RTRPV1MAPTERCC1ERCC4 | |
| SCHEMBL8804954 | 0.80 | GAA (0.35) | F2RTRPV1MAPTERCC1ERCC4 | |
| SCHEMBL8803620 | 0.77 | GAA (0.36) | MAPTGAAKMT2AALDH1A1LMNA | |
| SCHEMBL8804222 | 0.76 | MCHR1 (0.39) | F2RTRPV1CCKARCCKBRGAA | |
| SCHEMBL8806409 | 0.73 | HDAC8 (0.45) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8804470 | 0.71 | OPRM1 (0.41) | GAAKMT2AALDH1A1LMNAHTT | |
| SCHEMBL8805179 | 0.70 | OPRL1 (0.35) | F2RCCKARCCKBRGAAKMT2A | |
| SCHEMBL8805028 | 0.69 | SLC6A3 (0.43) | MAPTRAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL8803886 | 0.67 | TRPV1 (0.33) | TRPV1GAAKMT2AALDH1A1LMNA | |
| SCHEMBL8804530 | 0.65 | GAA (0.40) | F2RGAAKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-5621010-A | ANTIHYPERCHOLESTEROLEMIA AND ANTIATHEROSCLEROSIS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0625507-A2 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1994-11-23 | — | — | EP | disclosed |