SCHEMBL880503

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30527730	0.91	HSD11B1 (0.57)	CTSKHSD11B1CYP2C9EPHX1CA1
	SCHEMBL31250358	0.91	HSD11B1 (0.57)	CTSKHSD11B1CYP2C9EPHX1CA1
	SCHEMBL6586590	0.89	DRD2 (0.49)	CTSKHSD11B1CYP2C9EPHX1CA1
	SCHEMBL4760650	0.85	CTSK (0.50)	CTSKHSD11B1CYP2C9EPHX1CA1
	SCHEMBL13666827	0.84	TSHR (0.57)	CTSKHSD11B1CYP2C9EPHX1CA1
	SCHEMBL89460	0.83	EPHX2 (0.56)	CTSKHSD11B1CYP2C9EPHX1CA1
	SCHEMBL6187601	0.83	CTSK (0.56)	CTSKHSD11B1CYP2C9EPHX1CA1
	SCHEMBL18926997	0.83	EPHX1 (0.70)	CTSKHSD11B1CYP2C9EPHX1CA1
	SCHEMBL27408850	0.83	CTSK (0.56)	CTSKHSD11B1CYP2C9EPHX1CA1
	SCHEMBL4760808	0.82	CTSK (0.50)	CTSKHSD11B1CYP2C9EPHX1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.