Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806241 | 1.00 | STAT3 (0.43) | STAT3RAB9ALMNAALDH1A1FBP1 | |
| SCHEMBL5093403 | 0.86 | STAT3 (0.49) | STAT3RAB9ALMNAALDH1A1FBP1 | |
| SCHEMBL8915195 | 0.79 | STAT3 (0.45) | STAT3RAB9ALMNAALDH1A1FBP1 | |
| SCHEMBL3173742 | 0.79 | ALDH1A1 (0.50) | STAT3RAB9ALMNAALDH1A1BACE1 | |
| SCHEMBL8915201 | 0.79 | STAT3 (0.45) | STAT3RAB9ALMNAALDH1A1FBP1 | |
| SCHEMBL3159031 | 0.79 | RAB9A (0.48) | STAT3RAB9ALMNAALDH1A1FBP1 | |
| SCHEMBL3159026 | 0.79 | RAB9A (0.48) | STAT3RAB9ALMNAALDH1A1FBP1 | |
| SCHEMBL3173753 | 0.79 | ALDH1A1 (0.50) | STAT3RAB9ALMNAALDH1A1BACE1 | |
| SCHEMBL4876757 | 0.78 | STAT3 (0.52) | STAT3RAB9ALMNAALDH1A1FBP1 | |
| SCHEMBL4876750 | 0.78 | STAT3 (0.52) | STAT3RAB9ALMNAALDH1A1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583136-B1 | Piperidino-3,4-dihydrocarbostyryl compounds for the treatment of ischemic disorders | KISSEI PHARMACEUTICAL (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5294718-A | Platelet aggregation inhibitors; antiischemic agents; side effect reduction | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0583136-A2 | Piperidino-3,4-dihydrocarbostyryl compounds for the treatment of ischemic disorders | Kissei Pharmaceutical Co., Ltd. (JP) | 1994-02-16 | — | — | EP | disclosed |