SCHEMBL880688

SCHEMBL880688

O=C(O)CC(O)(CC(=O)O)CC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
HMGCR P04035 1/20 0.56
CHRM1 P11229 1/20 0.56
TBXA2R P21731 1/20 0.56
ADRA1A P35348 1/20 0.56
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
HIF1A Q16665 1/20 0.45
ACLY P53396 3/20 0.43
CPT2 P23786 2/20 0.42
KDM4E B2RXH2 1/20 0.39
FFAR1 O14842 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
LMNA P02545 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30017023 0.96 ALDH1A1 (0.53) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL29363039 0.96 ALDH1A1 (0.53) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Ammonia Solution, Strong SCHEMBL29372545 0.93 ALDH1A1 (0.50) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
Water SCHEMBL29581041 0.93 ALDH1A1 (0.50) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL7039700 0.83 ALDH1A1 (0.48) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL2421001 0.81 HMGCR (0.52) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL380759 0.81 HMGCR (0.52) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL11507779 0.81 MVD (0.47) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL15728325 0.81 ALDH1A1 (0.40) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL7654599 0.78 ALDH1A1 (0.43) ALDH1A1HMGCRCHRM1TBXA2RADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025224437-A1 BIOMARKERS FOR LUNG CANCER ABERYSTWYTH UNIVERSITY (GB) 2025-10-30 WO claimed
EP-3707193-A1 DENDRIMER DELIVERY SYSTEM AND METHODS OF USE THEREOF The Johns Hopkins University (US) 2020-09-16 EP claimed
CN-111615528-A Dendrimer delivery systems and methods of use thereof 约翰霍普金斯大学 2020-09-01 CN claimed
US-20190142964-A1 DENDRIMER DELIVERY SYSTEM AND METHODS OF USE THEREOF Ashvattha Therapeutics, Inc. 2019-05-16 US claimed
EP-1070748-A1 Powder coating compositions, their preparation and use E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-01-24 EP claimed
US-6114489-A POWDER COATING COMPOSITIONS CONTAINING NOVEL ALIPHATIC HYPERBRANCHED POLYESTER POLYMERS, WHICH FUNCTION EITHER AS POLYMERIC CROSSLINKERS OR AS FLOW AND LEVELING AGENTS HERBERTS GMBH (DE) 2000-09-05 US claimed
US-20260102502-A1 CANNABINOID DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY UNIV JOHNS HOPKINS (US) 2026-04-16 US disclosed
US-20250352653-A1 NEURON TARGETED 2-DEOXYGLUCOSE DENDRIMER FOR IMAGING AND TREATMENT OF NEUROLOGICAL DISEASES UNIV WASHINGTON STATE (US) 2025-11-20 US disclosed
WO-2025224437-A1 BIOMARKERS FOR LUNG CANCER ABERYSTWYTH UNIVERSITY (GB) 2025-10-30 WO disclosed
WO-2025224437-A1 BIOMARKERS FOR LUNG CANCER ABERYSTWYTH UNIVERSITY (GB) 2025-10-30 WO disclosed
US-20250269044-A1 PSMA-TARGETED DENDRIMER NANOPLATFORM FOR CANCER DETECTION AND THERAPY WASHINGTON STATE UNIVERSITY 2025-08-28 US disclosed
EP-4577246-A1 DENDRIMER CONJUGATES OF ANTIDEPRESSANT AND ANTIPSYCHOTIC AGENTS AND THEIR METHODS OF USE The Johns Hopkins University (US) 2025-07-02 EP disclosed
EP-4577245-A1 DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY OF PSYCHEDELIC THERAPEUTICS The Johns Hopkins University (US) 2025-07-02 EP disclosed
US-20090239949-A1 Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same SHIRE LLC 2009-09-24 US disclosed
US-20090239949-A1 Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same SHIRE LLC 2009-09-24 US disclosed
US-20080207757-A1 Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-08-28 US disclosed
US-20080207757-A1 Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-08-28 US disclosed
WO-2008098151-A2 POLAR HYDROPHILIC PRODRUGS OF AMPHETAMINE AND OTHER STIMULANTS AND PROCESSES FOR MAKING AND USING THE SAME KEMPHARM, INC. (US) 2008-08-14 WO disclosed
EP-1070748-A1 Powder coating compositions, their preparation and use E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-01-24 EP disclosed
US-6114489-A POWDER COATING COMPOSITIONS CONTAINING NOVEL ALIPHATIC HYPERBRANCHED POLYESTER POLYMERS, WHICH FUNCTION EITHER AS POLYMERIC CROSSLINKERS OR AS FLOW AND LEVELING AGENTS HERBERTS GMBH (DE) 2000-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090239949-A1 Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same SLC6A2, SLC6A3, SLC18A2 ALDH1A1 1191/4885HMGCR 2980/4885CHRM1 60/4885
US-20190142964-A1 DENDRIMER DELIVERY SYSTEM AND METHODS OF USE THEREOF TLR3, CD40LG, OXGR1 ALDH1A1 2712/4885HMGCR 2130/4885CHRM1 685/4885
US-20260102502-A1 CANNABINOID DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY CNR1, CNR2, GPR18 ALDH1A1 3449/4885HMGCR 3182/4885CHRM1 547/4885
US-20080207757-A1 Polar Hydrophilic Prodrugs of Amphetamine and Other Stimulants and Processes for Making and Using the Same SLC6A2, SLC6A3, SLC18A2 ALDH1A1 1191/4885HMGCR 2980/4885CHRM1 60/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.