Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.43 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734922 | 0.88 | ACHE (0.52) | ACHENQO1MAOBKDM4EMEN1 | |
| SCHEMBL6738549 | 0.86 | ACHE (0.51) | ACHENQO1MAOBKDM4EMEN1 | |
| SCHEMBL8808189 | 0.83 | KDM4E (0.53) | ACHEKDM4EMEN1MAPTKMT2A | |
| SCHEMBL8807846 | 0.82 | ACHE (0.48) | ACHENQO1MAOBKDM4EMEN1 | |
| SCHEMBL8806711 | 0.81 | ALDH1A1 (0.59) | NQO1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL8807799 | 0.81 | ALDH1A1 (0.62) | NQO1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL9144825 | 0.80 | NQO1 (0.50) | ACHENQO1KDM4EMAPTALDH1A2 | |
| SCHEMBL8745776 | 0.78 | NQO1 (0.59) | ACHENQO1KDM4EMEN1MAPT | |
| SCHEMBL8807035 | 0.78 | ALDH1A1 (0.58) | KDM4EMEN1MAPTKMT2AALDH1A2 | |
| SCHEMBL8745814 | 0.77 | NQO1 (0.52) | ACHENQO1KDM4EMAPTALDH1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584091-B1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | SCHWABE WILLMAR GMBH & CO (DE) | 1997-01-15 | — | — | EP | disclosed |
| US-5428038-A | Administering for preventing or treating N-methyl-D-aspartate induced convulsions | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0584091-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF. | SCHWABE WILLMAR GMBH & CO (DE) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992018493-A1 | BENZOPYRANONES, METHODS OF MANUFACTURE AND USE THEREOF | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1992-10-29 | — | — | WO | disclosed |