Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.46 |
| ▸ | ALDH1B1 | P30837 | 2/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745776 | 0.92 | NQO1 (0.59) | NQO1POLBMAPTALDH1A1ALDH1A2 | |
| SCHEMBL9144825 | 0.91 | NQO1 (0.50) | NQO1POLBMAPTALDH1A1ALDH1A2 | |
| SCHEMBL8745815 | 0.84 | NQO1 (0.51) | NQO1POLBMAPTALDH1A1ALDH1A2 | |
| SCHEMBL8745806 | 0.84 | NQO1 (0.52) | NQO1POLBMAPTALDH1A1ALDH1A2 | |
| SCHEMBL8745768 | 0.83 | NQO1 (0.44) | NQO1POLBMAPTALDH1A1ALDH1A2 | |
| SCHEMBL9148098 | 0.80 | ALDH1A1 (0.48) | NQO1POLBMAPTALDH1A1ALDH1A2 | |
| SCHEMBL8807713 | 0.80 | ALDH1A1 (0.48) | NQO1POLBMAPTALDH1A1ALDH1A2 | |
| SCHEMBL8745793 | 0.79 | NQO1 (0.56) | NQO1POLBMAPTALDH1A1ALDH1A2 | |
| SCHEMBL8807147 | 0.77 | ACHE (0.53) | NQO1MAPTALDH1A2ALDH2ALDH1B1 | |
| SCHEMBL9080519 | 0.76 | NQO1 (0.58) | NQO1POLBMAPTALDH1A1ALDH1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0663911-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE. | SCHWABE WILLMAR GMBH & CO (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008985-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1994-04-28 | — | — | WO | disclosed |