Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 4/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810776 | 0.82 | EDNRA (0.44) | EDNRAHSD17B10KDM4ETP53SMN1; SMN2 | |
| SCHEMBL7987355 | 0.76 | OGA (0.43) | EDNRAHSD17B10KDM4ETP53SMN1; SMN2 | |
| SCHEMBL8789026 | 0.69 | RAB9A (0.55) | EDNRAKDM4ESMN1; SMN2OGAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7987566 | 0.69 | MAPK9 (0.39) | EDNRAOGAALDH1A1KMT2AHPGD | |
| SCHEMBL7987498 | 0.68 | RAB9A (0.48) | KDM4EOGAALDH1A1KMT2AHPGD | |
| SCHEMBL6138702 | 0.68 | RAB9A (0.56) | EDNRAKDM4ESMN1; SMN2OGAALDH1A1 | |
| SCHEMBL12053329 | 0.67 | CYP3A4 (0.55) | OGAKMT2AHPGDMEN1RAB9A | |
| SCHEMBL7502509 | 0.66 | RAB9A (0.53) | KDM4EOGAKMT2AHPGDMEN1 | |
| SCHEMBL7332440 | 0.66 | CYP3A4 (0.53) | EDNRAKDM4EOGAKMT2AHPGD | |
| SCHEMBL27537606 | 0.66 | EDNRA (0.55) | EDNRAKDM4EKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792265-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-03 | — | — | EP | disclosed |