Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 6/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809508 | 0.91 | TP53 (0.50) | HTR2CGAANPSR1UBE2MDCUN1D1 | |
| SCHEMBL8809108 | 0.90 | GAA (0.48) | GAANPSR1UBE2MDCUN1D1TP53 | |
| SCHEMBL9057173 | 0.90 | TP53 (0.51) | HTR2CGAANPSR1UBE2MDCUN1D1 | |
| SCHEMBL8814133 | 0.87 | THRB (0.49) | GAANPSR1UBE2MDCUN1D1TP53 | |
| SCHEMBL8807322 | 0.86 | GAA (0.46) | GAANPSR1UBE2MDCUN1D1TP53 | |
| SCHEMBL8810779 | 0.85 | NPSR1 (0.47) | GAANPSR1UBE2MDCUN1D1TP53 | |
| SCHEMBL8807965 | 0.85 | GAA (0.47) | GAANPSR1UBE2MDCUN1D1TP53 | |
| SCHEMBL8808422 | 0.83 | TP53 (0.52) | GAANPSR1UBE2MDCUN1D1TP53 | |
| SCHEMBL9057006 | 0.83 | LMNA (0.49) | GAANPSR1UBE2MDCUN1D1TP53 | |
| SCHEMBL8808845 | 0.81 | GAA (0.51) | GAANPSR1UBE2MDCUN1D1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |