Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | TDO2 | P48775 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30012260 | 1.00 | TDP1 (0.54) | TDP1HPRT1CTSBSIRT2TSHR | |
| SCHEMBL29493152 | 1.00 | TDP1 (0.54) | TDP1HPRT1CTSBSIRT2TSHR | |
| SCHEMBL6245129 | 0.79 | HPRT1 (0.78) | TDP1HPRT1CTSBSIRT2TSHR | |
| SCHEMBL12712555 | 0.76 | TDP1 (0.54) | TDP1HPRT1CTSBSIRT2TSHR | |
| SCHEMBL5624830 | 0.76 | TDP1 (0.54) | TDP1HPRT1CTSBSIRT2TSHR | |
| SCHEMBL29401731 | 0.76 | CASP6 (0.62) | TDP1HPRT1CTSBSIRT2TSHR | |
| SCHEMBL414254 | 0.76 | TDP1 (0.54) | TDP1HPRT1CTSBSIRT2TSHR | |
| SCHEMBL11335429 | 0.76 | CTSB (0.61) | TDP1HPRT1CTSBSIRT2TSHR | |
| SCHEMBL8687725 | 0.76 | CTSB (0.77) | TDP1HPRT1CTSBSIRT2TSHR | |
| SCHEMBL29378223 | 0.76 | TDP1 (0.54) | TDP1HPRT1CTSBSIRT2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232010-A | Method for preparing 1-fluoro-4-nitronaphthalene through microchannel reaction | 中国科学技术大学先进技术研究院 | 2022-10-25 | — | — | CN | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| EP-0696289-A1 | BENZO F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |