Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805003 | 0.88 | CCR1 (0.55) | CCR1MAPTKDM4ETSHRACHE | |
| SCHEMBL8807153 | 0.87 | CCR1 (0.54) | CCR1KDM4ETSHRACHEALDH1A1 | |
| SCHEMBL9719915 | 0.79 | CCR1 (0.48) | CCR1MAPTKDM4EACHEALDH1A1 | |
| SCHEMBL8803420 | 0.76 | MAPT (0.51) | MAPTKDM4ESYKTSHRMEN1 | |
| SCHEMBL11007383 | 0.75 | ACHE (0.73) | MAPTKDM4ETSHRACHEMEN1 | |
| Hydrochloric Acid SCHEMBL8807109 | 0.75 | TSHR (0.52) | MAPTKDM4ESYKTSHRMEN1 | |
| SCHEMBL11648357 | 0.74 | ACHE (0.50) | CCR1MAPTKDM4EACHEMEN1 | |
| SCHEMBL10910082 | 0.73 | PTGS2 (0.47) | CCR1MAPTACHEL3MBTL1 | |
| SCHEMBL29061980 | 0.73 | PTGS2 (0.47) | CCR1MAPTACHEL3MBTL1 | |
| SCHEMBL9449932 | 0.72 | ALDH1A1 (0.55) | CCR1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633288-A | EXPECTORANT | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| EP-0555481-B1 | TRI(C1-C6 ALKOXY)BENZENE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5498635-A | RESPIRATORY DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| US-5401775-A | Pulmonary surfactant secretion promoter | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0555481-A1 | TRI(C1-C6 ALKOXY)BENZENE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |