Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807702 | 0.89 | KMT2A (0.64) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8805985 | 0.84 | TP53 (0.57) | KMT2AMEN1ALDH1A1CYP19A1RXFP1 | |
| SCHEMBL8416372 | 0.81 | YES1 (0.67) | KMT2AMEN1ALDH1A1HTTCYP19A1 | |
| SCHEMBL24480054 | 0.80 | LMNA (0.52) | KMT2AMEN1ALDH1A1HTR2CLMNA | |
| SCHEMBL8805573 | 0.80 | HTR2C (0.71) | GAAALDH1A1HTR2CLMNAKDM4E | |
| SCHEMBL9056948 | 0.78 | POLB (0.53) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL24479862 | 0.78 | MAPT (0.52) | KMT2AMEN1ALDH1A1LMNAKDM4E | |
| SCHEMBL1233547 | 0.78 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL7552365 | 0.77 | KMT2A (0.56) | KMT2AMEN1ALDH1A1LMNARXFP1 | |
| SCHEMBL1233342 | 0.76 | HDAC1 (0.62) | KMT2AMEN1ALDH1A1LMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |