Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755097 | 0.72 | TSHR (0.46) | KMT2ANT5EGAANSD2PLCG1 | |
| SCHEMBL8807829 | 0.70 | HSD17B10 (0.56) | LMNAMCL1CYP1A2CYP2C9MAOA | |
| SCHEMBL10393914 | 0.69 | TSHR (0.46) | KMT2ANT5EGAANSD2PLCG1 | |
| SCHEMBL11846196 | 0.65 | NQO1 (0.58) | ESR2ESR1MCL1MAOAKDM4E | |
| SCHEMBL3192233 | 0.65 | GAA (0.47) | KDM4EKMT2ANT5EGAANSD2 | |
| SCHEMBL428171 | 0.64 | TSHR (0.39) | CYP2C9CYP2C19KDM4EKMT2ANT5E | |
| SCHEMBL7821939 | 0.63 | TDP1 (0.35) | GAANSD2PLCG1DNMT1CASP6 | |
| SCHEMBL11596884 | 0.62 | NT5E (0.57) | CYP1A2CYP2C9CYP2C19KMT2ANT5E | |
| SCHEMBL31331777 | 0.62 | MCL1 (0.70) | LMNAMCL1CYP1A2MAOAKDM4E | |
| SCHEMBL8814191 | 0.62 | KDM4E (0.44) | LMNAMCL1CYP1A2MAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696157-A | Sulfonated derivatives of 7-aminocoumarin | MOLECULAR PROBES, INC. (US) | 1997-12-09 | — | — | US | disclosed |