Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 13/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343982 | 0.82 | CARM1 (0.52) | TRPA1MAPTCARM1PRMT6POLB | |
| SCHEMBL2783268 | 0.77 | POLB (0.60) | TRPA1MAPTCARM1PRMT6POLB | |
| SCHEMBL8343718 | 0.77 | MAPT (0.52) | TRPA1MAPTCARM1PRMT6POLB | |
| SCHEMBL14829704 | 0.77 | CES2 (0.47) | MAPTPOLBCYP2C19 | |
| SCHEMBL377060 | 0.73 | NAPRT (0.36) | MAPT | |
| SCHEMBL28822437 | 0.73 | MAPT (0.46) | TRPA1MAPTHTR1ASLC6A2SLC6A4 | |
| SCHEMBL1344279 | 0.71 | MAPT (0.44) | TRPA1MAPTCARM1PRMT6POLB | |
| SCHEMBL15074711 | 0.71 | TRPA1 (0.58) | TRPA1MAPTCARM1PRMT6POLB | |
| SCHEMBL11924845 | 0.71 | CARM1 (0.65) | TRPA1MAPTCARM1PRMT6POLB | |
| SCHEMBL400328 | 0.70 | TRPA1 (0.57) | TRPA1MAPTCARM1PRMT6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773934-A1 | HERBICIDAL PYRAZINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003391-A1 | HERBICIDAL PYRAZINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-08 | — | — | WO | disclosed |