Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.83 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864236 | 0.95 | HRH3 (0.72) | HRH3CXCR4RAB9APOLBHPGD | |
| SCHEMBL11434269 | 0.93 | HRH3 (0.69) | HRH3CXCR4RAB9AMEN1KMT2A | |
| SCHEMBL2731922 | 0.85 | ACHE (0.61) | HRH3RAB9AMEN1KMT2APOLB | |
| SCHEMBL10953965 | 0.85 | HRH3 (0.88) | HRH3CXCR4RAB9AMEN1KMT2A | |
| SCHEMBL24093171 | 0.84 | HRH3 (0.86) | HRH3CXCR4RAB9AMEN1KMT2A | |
| SCHEMBL8809487 | 0.84 | HRH3 (0.86) | HRH3CXCR4RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27669852 | 0.83 | RAB9A (0.61) | HRH3RAB9AMEN1KMT2APOLB | |
| SCHEMBL9057590 | 0.83 | HRH3 (0.83) | HRH3CXCR4RAB9AMEN1KMT2A | |
| SCHEMBL8809145 | 0.83 | POLB (0.83) | HRH3CXCR4RAB9AMEN1KMT2A | |
| SCHEMBL8806696 | 0.83 | HRH3 (0.83) | HRH3CXCR4RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |