Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | BRS3 | P32247 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23124608 | 0.93 | MEN1 (0.61) | HRH3KMT2AMEN1RAB9ATGFBR1 | |
| SCHEMBL18984688 | 0.83 | MAP4K4 (0.56) | HRH3KMT2AMEN1RAB9APOLB | |
| SCHEMBL7695218 | 0.81 | ACHE (0.69) | KMT2AMEN1 | |
| SCHEMBL18129094 | 0.81 | MAP4K4 (0.56) | HRH3KMT2AMEN1RAB9APOLB | |
| SCHEMBL8809487 | 0.80 | HRH3 (0.86) | HRH3KMT2AMEN1RAB9APOLB | |
| SCHEMBL24093171 | 0.80 | HRH3 (0.86) | HRH3KMT2AMEN1RAB9APOLB | |
| SCHEMBL16249332 | 0.78 | MEN1 (0.83) | HRH3KMT2AMEN1RAB9APOLB | |
| SCHEMBL18984676 | 0.78 | MAP4K4 (0.57) | TGFBR1KDM4EALDH1A1PKM | |
| SCHEMBL10953965 | 0.78 | HRH3 (0.88) | HRH3KMT2AMEN1RAB9APOLB | |
| SCHEMBL24574127 | 0.76 | HRH3 (0.71) | HRH3KMT2AMEN1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |