Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971718 | 0.74 | NPSR1 (0.42) | NPSR1KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8806290 | 0.74 | L3MBTL1 (0.47) | NPSR1KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3097821 | 0.74 | — | — | |
| SCHEMBL2441537 | 0.67 | NPSR1 (0.47) | NPSR1KDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL23538248 | 0.67 | NPSR1 (0.46) | NPSR1KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL952325 | 0.67 | ALDH1A1 (0.56) | NPSR1KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2447674 | 0.67 | MAPT (0.41) | NPSR1MAPTALDH1A1SMN1; SMN2PKM | |
| SCHEMBL9860580 | 0.67 | NPSR1 (0.52) | NPSR1KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9091123 | 0.66 | NPSR1 (0.71) | NPSR1KDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2439659 | 0.66 | NPSR1 (0.45) | NPSR1KDM4EALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476456-B1 | Substituted 2-thiazolyl tetrazolium salt indicators | BAYER AG (US) | 1997-11-12 | — | — | EP | disclosed |
| EP-0476454-B1 | Analytical method using tetrazolium salt indicators having a reflectance plateau | BAYER AG (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5126275-A | Chromogenic reducing indicators for reducing substances such as NADH | MILES INC. (US) | 1992-06-30 | — | — | US | disclosed |