Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HPGDS | O60760 | 7/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806346 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHPGDSF2GLA | |
| SCHEMBL755482 | 0.79 | KDM4E (0.54) | ALDH1A1HPGDHSD17B10ALOX15HPGDS | |
| SCHEMBL9319027 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10ALOX15GLA | |
| SCHEMBL1993328 | 0.78 | KDM4E (0.57) | ALDH1A1HPGDHSD17B10HPGDSF2 | |
| SCHEMBL9939626 | 0.77 | CHEK1 (0.63) | ALDH1A1HPGDSGLAPDGFRBPDGFRA | |
| SCHEMBL13666129 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDHPGDSF2GLA | |
| SCHEMBL11088871 | 0.77 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10ALOX15KDM4E | |
| SCHEMBL13905401 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10ALOX15GLA | |
| SCHEMBL6084225 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10ALOX15KDM4E | |
| SCHEMBL1208396 | 0.76 | ALOX15 (0.61) | ALDH1A1HPGDHSD17B10ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663179-A | CAN SENSITIZE MULTIDRUG RESISTANT CANCER CELLS TO CHEMOTHERAPEUTIC AGENTS | LABORATOIRES GLAXO SA (FR) | 1997-09-02 | — | — | US | disclosed |
| EP-0649410-B1 | ANILIDE DERIVATIVES | GLAXO LAB SA (FR) | 1997-05-02 | — | — | EP | disclosed |
| EP-0649410-A1 | ANILIDE DERIVATIVES. | GLAXO LAB SA (FR) | 1995-04-26 | — | — | EP | disclosed |
| WO-1994001408-A1 | ANILIDE DERIVATIVES | LABORATOIRES GLAXO S.A. (FR) | 1994-01-20 | — | — | WO | disclosed |