Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28479392 | 0.84 | NPC1 (0.50) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL27945624 | 0.82 | NPC1 (0.49) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL21346072 | 0.79 | TNIK (0.54) | MAP2K4SMN1; SMN2MAPK1TNIK | |
| SCHEMBL14069232 | 0.79 | SMN1; SMN2 (0.66) | NPC1MAPTRAB9ASMN1; SMN2AXL | |
| SCHEMBL8809534 | 0.76 | CHEK1 (0.51) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL3070625 | 0.76 | TRPM8 (0.62) | NPC1MAPTRAB9ASMN1; SMN2TRPM8 | |
| SCHEMBL4893890 | 0.76 | RAB9A (0.57) | NPC1MAPTRAB9ASMN1; SMN2TNIK | |
| SCHEMBL13514605 | 0.76 | SMN1; SMN2 (0.47) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL27883363 | 0.76 | SMN1; SMN2 (0.56) | NPC1MAPTRAB9AGFERSMN1; SMN2 | |
| SCHEMBL3228033 | 0.76 | MEN1 (0.61) | NPC1MAPTRAB9ASMN1; SMN2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |