SCHEMBL8808357

SCHEMBL8808357

Cc1cc(C)c(C(=O)N[C@@H](CN[C@H]2CCOC2O)CC(C)C)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 15/20 0.43
TAS1R3 Q7RTX0 4/20 0.39
TAS1R1 Q7RTX1 4/20 0.39
TAS1R2 Q8TE23 4/20 0.39
CAPNS1 P04632 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8809938 0.85 CAPN1 (0.41) CAPN1TAS1R3TAS1R1TAS1R2CAPNS1
SCHEMBL8408032 0.83 CAPN1 (0.51) CAPN1CAPNS1
SCHEMBL8810404 0.83 CAPN1 (0.46) CAPN1TAS1R3TAS1R1CAPNS1
SCHEMBL8810035 0.82 CAPN1 (0.52) CAPN1TAS1R3TAS1R1CAPNS1
SCHEMBL8807996 0.82 CAPN1 (0.50) CAPN1CAPNS1
SCHEMBL8808370 0.82 CAPN1 (0.62) CAPN1CAPNS1
SCHEMBL8808352 0.82 CAPN1 (0.62) CAPN1CAPNS1
SCHEMBL8810942 0.80 CAPN1 (0.44) CAPN1TAS1R3TAS1R1CAPNS1
SCHEMBL8809572 0.80 CAPN1 (0.50) CAPN1CAPNS1
SCHEMBL8404262 0.80 NR3C1 (0.43) CAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0810221-A1 OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES MITSUBISHI CHEMICAL CORPORATION (JP) 1997-12-03 EP disclosed