Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 9/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808791 | 0.89 | CTSL (0.48) | CAPN1CTSLHPGDCAPNS1CYP2C19 | |
| SCHEMBL8809572 | 0.88 | CAPN1 (0.50) | CAPN1CTSLCAPNS1CTSSCTSK | |
| SCHEMBL8408032 | 0.87 | CAPN1 (0.51) | CAPN1HPGDCAPNS1CTSSCTSK | |
| SCHEMBL8810404 | 0.87 | CAPN1 (0.46) | CAPN1TAS1R3TAS1R1CAPNS1 | |
| SCHEMBL8812456 | 0.85 | CASP1 (0.52) | CAPN1CAPNS1CTSK | |
| SCHEMBL8810040 | 0.83 | CAPN1 (0.70) | CAPN1CTSLCAPNS1CTSSCTSK | |
| SCHEMBL8810031 | 0.83 | CAPN1 (0.70) | CAPN1CTSLCAPNS1CTSSCTSK | |
| SCHEMBL8810535 | 0.82 | CAPN1 (0.52) | CAPN1CTSLHPGDCAPNS1ALDH1A1 | |
| SCHEMBL8808357 | 0.82 | CAPN1 (0.43) | CAPN1TAS1R3TAS1R1CAPNS1 | |
| SCHEMBL8404255 | 0.82 | HTT (0.46) | CAPN1TAS1R3TAS1R1CAPNS1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |