Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 15/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404255 | 0.90 | HTT (0.46) | CAPN1CAPNS1NPC1RAB9A | |
| SCHEMBL8810535 | 0.90 | CAPN1 (0.52) | CAPN1CAPNS1HPGD | |
| SCHEMBL8809572 | 0.90 | CAPN1 (0.50) | CAPN1CAPNS1CTSSCTSK | |
| SCHEMBL8807780 | 0.89 | TAS1R3 (0.46) | CAPN1CAPNS1CTSS | |
| SCHEMBL8810404 | 0.88 | CAPN1 (0.46) | CAPN1CAPNS1 | |
| SCHEMBL8812425 | 0.88 | CAPN1 (0.53) | CAPN1L3MBTL1CAPNS1HPGDSMN1; SMN2 | |
| SCHEMBL8809378 | 0.88 | HDAC4 (0.42) | CAPN1CAPNS1NPC1RAB9A | |
| SCHEMBL8810035 | 0.87 | CAPN1 (0.52) | CAPN1CAPNS1HPGDNPC1CYP2C19 | |
| SCHEMBL8810413 | 0.86 | TAS1R3 (0.49) | CAPN1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8812456 | 0.84 | CASP1 (0.52) | CAPN1CAPNS1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |