Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829348 | 0.83 | S1PR4 (0.39) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL8808836 | 0.79 | LMNA (0.46) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL5267218 | 0.79 | MAPT (0.41) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL18031283 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL30622635 | 0.78 | LMNA (0.40) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL4829285 | 0.78 | MAPT (0.38) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL7220392 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL7220292 | 0.74 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL8814038 | 0.72 | LMNA (0.43) | ALDH1A1MAPTLMNAHTTKMT2A | |
| SCHEMBL9121830 | 0.70 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |