SCHEMBL8808481

SCHEMBL8808481

Cc1ccc(C(O)c2cccc(Oc3ccccc3)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.54
SRD5A2 P31213 1/20 0.51
MEN1 O00255 1/20 0.49
CYP2D6 P10635 1/20 0.49
KMT2A Q03164 1/20 0.49
ALOX5 P09917 1/20 0.47
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ACACB O00763 1/20 0.42
ACACA Q13085 1/20 0.42
NPY5R Q15761 1/20 0.41
BRD4 O60885 1/20 0.41
CREBBP Q92793 1/20 0.41
AKR1C3 P42330 1/20 0.41
MAOB P27338 1/20 0.41
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL477413 0.90 PTGS1 (0.59) PTGS1SRD5A2MEN1CYP2D6KMT2A
SCHEMBL13886755 0.90 PTGS1 (0.59) PTGS1SRD5A2MEN1CYP2D6KMT2A
SCHEMBL8895993 0.88 PTGS1 (0.61) PTGS1SRD5A2MEN1CYP2D6KMT2A
SCHEMBL477692 0.80 SRD5A2 (0.72) PTGS1SRD5A2SMN1; SMN2ACACBACACA
SCHEMBL477590 0.80 LMNA (0.50) CYP2D6KMT2ASMN1; SMN2L3MBTL1
SCHEMBL477533 0.80 LMNA (0.50) CYP2D6KMT2ASMN1; SMN2L3MBTL1
SCHEMBL477385 0.80 LMNA (0.50) CYP2D6KMT2ASMN1; SMN2L3MBTL1
SCHEMBL21133961 0.78 SRD5A2 (0.75) SRD5A2ACACBACACA
SCHEMBL10547121 0.78 PTGS1 (0.67) PTGS1MEN1CYP2D6KMT2AALOX5
SCHEMBL2353755 0.78 PTGS1 (0.67) PTGS1MEN1CYP2D6KMT2AALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0801048-A1 Process for producing benzhydrols K I CHEMICAL INDUSTRY CO., LTD. (JP) 1997-10-15 EP disclosed