Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MLKL | Q8NB16 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477533 | 1.00 | LMNA (0.50) | LMNAMLKLSMN1; SMN2TSHRALOX12 | |
| SCHEMBL477590 | 1.00 | LMNA (0.50) | LMNAMLKLSMN1; SMN2TSHRALOX12 | |
| SCHEMBL3863823 | 0.93 | CA12 (0.55) | LMNAMLKLSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL96180 | 0.89 | ACHE (0.50) | LMNAMLKLTSHRACHECYP3A4 | |
| Hydrochloric Acid SCHEMBL29699724 | 0.87 | ACHE (0.47) | LMNAMLKLTSHRACHECYP3A4 | |
| SCHEMBL8671295 | 0.87 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2TSHRCYP2D6CA12 | |
| SCHEMBL12378742 | 0.86 | LMNA (0.41) | LMNAMLKLSMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL6878032 | 0.85 | LMNA (0.54) | LMNATSHRALOX12ACHECYP3A4 | |
| Diphenylmethanol SCHEMBL6434457 | 0.84 | SMN1; SMN2 (0.61) | LMNASMN1; SMN2TSHRCYP2D6CA12 | |
| Diphenylmethanol SCHEMBL11564700 | 0.84 | SMN1; SMN2 (0.61) | LMNASMN1; SMN2TSHRCYP2D6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785688-B1 | A PROCESS FOR THE MANUFACTURE OF CHIRAL CATALYSTS AND THEIR SALTS | SCINOPHARM TAIWAN LTD (TW) | 2017-09-13 | — | — | EP | disclosed |
| CN-103974932-B | Preparation method of chiral catalyst and salt thereof | SCINOPHARM TAIWAN, LTD. (CN) | 2016-05-18 | — | — | CN | disclosed |
| US-8859765-B2 | Process for the manufacture of chiral catalysts and their salts | SCINOPHARM TAIWAN, LTD. (TW) | 2014-10-14 | — | — | US | disclosed |
| CN-103974932-A | Preparation method of chiral catalyst and salt thereof | SCINOPHARM TAIWAN LTD | 2014-08-06 | — | — | CN | disclosed |
| US-8563786-B2 | Method for producing optically active alcohol | MITSUI CHEMICALS, INC. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20130150574-A1 | PROCESS FOR THE MANUFACTURE OF CHIRAL CATALYSTS AND THEIR SALTS | SCINOPHARM TAIWAN, LTD. (TW) | 2013-06-13 | — | — | US | disclosed |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-04-12 | — | — | US | disclosed |
| EP-2412694-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | Mitsui Chemicals, Inc. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-7592487-B2 | Chiral tertiary aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-09-22 | — | — | US | disclosed |
| US-7592487-B2 | Chiral tertiary aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-09-22 | — | — | US | disclosed |
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2008-02-21 | — | — | US | disclosed |
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150574-A1 | PROCESS FOR THE MANUFACTURE OF CHIRAL CATALYSTS AND THEIR SALTS | TST, TMT1A, MPST | LMNA 4802/4885MLKL 4595/4885SMN1; SMN2 3491/4885 |
| US-20080045757-A1 | Chiral Tertiary Aminoalkylnaphthols | ALDH7A1, ADH5, ALDH1A1 | LMNA 3053/4885MLKL 4852/4885SMN1; SMN2 4808/4885 |
| US-20120088938-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL | ADH1A, ADH1C, FHIT | LMNA 1422/4885MLKL 2292/4885SMN1; SMN2 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.