SCHEMBL477590

SCHEMBL477590

Cc1ccc(C(O)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
MLKL Q8NB16 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 2/20 0.48
ALOX12 P18054 1/20 0.48
ACHE P22303 1/20 0.48
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KEAP1 Q14145 1/20 0.45
NFE2L2 Q16236 1/20 0.45
CNR2 P34972 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL477533 1.00 LMNA (0.50) LMNAMLKLSMN1; SMN2TSHRALOX12
SCHEMBL477385 1.00 LMNA (0.50) LMNAMLKLSMN1; SMN2TSHRALOX12
SCHEMBL3863823 0.93 CA12 (0.55) LMNAMLKLSMN1; SMN2CYP3A4CYP2D6
SCHEMBL96180 0.89 ACHE (0.50) LMNAMLKLTSHRACHECYP3A4
Hydrochloric Acid SCHEMBL29699724 0.87 ACHE (0.47) LMNAMLKLTSHRACHECYP3A4
SCHEMBL8671295 0.87 SMN1; SMN2 (0.58) LMNASMN1; SMN2TSHRCYP2D6CA12
SCHEMBL12378742 0.86 LMNA (0.41) LMNAMLKLSMN1; SMN2TSHRCYP3A4
SCHEMBL6878032 0.85 LMNA (0.54) LMNATSHRALOX12ACHECYP3A4
Diphenylmethanol SCHEMBL6434457 0.84 SMN1; SMN2 (0.61) LMNASMN1; SMN2TSHRCYP2D6CA12
Diphenylmethanol SCHEMBL11564700 0.84 SMN1; SMN2 (0.61) LMNASMN1; SMN2TSHRCYP2D6CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528773-A N-alkylation method of sulfonamide compound 赣南医科大学 2025-02-28 CN claimed
CN-112517060-B Catalyst, application and synthesis method of 4-hydroxycoumarin derivative 山东农业大学 2022-03-25 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
EP-1075833-B1 Barrier cream SECR DEFENCE (GB) 2005-04-13 EP claimed
US-6319310-B1 FOR ACOUSTIC INK JET PRINTING; TRANSPARENCY, GLOSS, CREASE RESISTANCE XEROX CORPORATION 2001-11-20 US claimed
US-6309631-B1 OIL-BASED BASE CREAM, 40-50% W/W OF A 1:1 W/W MIXTURE OF TITANIUM DIOXIDE AND FERRIC OXIDE AND FROM 0 TO 20% W/W OF A MELT ADDITIVE; MITIGATION OF BURNS SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 2001-10-30 US claimed
EP-1075833-A1 Barrier cream THE SECRETARY OF STATE FOR DEFENCE (GB) 2001-02-14 EP claimed
US-6132499-A Inks XEROX CORPORATION (US) 2000-10-17 US claimed
US-6071333-A Ink compositions XEROX CORPORATION (US) 2000-06-06 US claimed
US-6066200-A COMPRISING A SOLID UREA COMPOUND, AN ALCOHOL, A LIGHTFASTNESS COMPONENT, A LIGHTFAST ANTIOXIDANT, AND A COLORANT XEROX CORPORATION (US) 2000-05-23 US claimed
US-5663022-A Recording sheets XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0677076-B1 DIARYL CARBINOL METATHESIS CATALYSTS SHELL OIL CO (US) 1997-04-16 EP claimed
EP-0686635-A1 Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses Sankyo Company Limited (JP) 1995-12-13 EP claimed
US-5470851-A Antihistamine, anticoagulants SANKYO COMPANY, LIMITED (JP) 1995-11-28 US claimed
EP-0677076-A1 DIARYL CARBINOL METATHESIS CATALYSTS. SHELL OIL CO (US) 1995-10-18 EP claimed
EP-0674232-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
WO-1994015989-A1 DIARYL CARBINOL METATHESIS CATALYSTS SHELL OIL COMPANY (US) 1994-07-21 WO claimed
US-5276118-A Metal complex SHELL OIL COMPANY (US) 1994-01-04 US claimed
EP-0549364-A1 Pyridylthiazolidinecarboxylic acid amide derivatives, their preparation and their therapeutic uses Sankyo Company Limited (JP) 1993-06-30 EP claimed