Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | GOT1 | P17174 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2488955 | 0.98 | LMNA (0.51) | LMNAPOLBALDH1A1MAPK1CYP1A2 | |
| SCHEMBL8811067 | 0.86 | ALDH1A1 (0.48) | LMNAPOLBALDH1A1MAPK1CYP1A2 | |
| SCHEMBL8809641 | 0.79 | ALDH1A1 (0.59) | LMNAPOLBALDH1A1MAPK1CYP1A2 | |
| SCHEMBL29674926 | 0.79 | ALDH1A1 (0.59) | LMNAPOLBALDH1A1MAPK1CYP1A2 | |
| SCHEMBL9461493 | 0.79 | LMNA (0.56) | LMNAPOLBALDH1A1MAPK1CYP1A2 | |
| SCHEMBL16115497 | 0.78 | ALDH1A1 (0.56) | LMNAPOLBALDH1A1CYP1A2HTT | |
| SCHEMBL599375 | 0.77 | LMNA (0.51) | LMNAPOLBALDH1A1MAPK1CYP1A2 | |
| SCHEMBL8129269 | 0.76 | CYP1A2 (0.42) | LMNAPOLBALDH1A1MAPK1CYP1A2 | |
| SCHEMBL30418421 | 0.76 | CYP1A2 (0.42) | LMNAPOLBALDH1A1MAPK1CYP1A2 | |
| SCHEMBL21965729 | 0.75 | LMNA (0.43) | LMNAPOLBALDH1A1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539805-B1 | Phthalazines substituted on position 1 by an ether group and process for their preparation | ASTA MEDICA AG (DE) | 1997-09-03 | — | — | EP | claimed |
| US-5354750-A | Analgesics, antinflammatory, anticonvulsive and antipyretic agents | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | claimed |
| EP-0539805-A1 | Phthalazines substituted on position 1 by an ether or a thioether group and process for their preparation | ASTA Medica Aktiengesellschaft (DE) | 1993-05-05 | — | — | EP | claimed |
| JP-5222002-A | — | — | None | — | — | JP | disclosed |
| EP-0539805-B1 | Phthalazines substituted on position 1 by an ether group and process for their preparation | ASTA MEDICA AG (DE) | 1997-09-03 | — | — | EP | disclosed |
| US-5354750-A | Analgesics, antinflammatory, anticonvulsive and antipyretic agents | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | disclosed |
| JP-H05222002-A | PHTHALAZINE CONTAINING ETHER OR THIOETHER GROUP IN 1-POSITION, ITS PREPARATION AND PHARMACEUTICAL CONTAINING THE SAME, WHICH HAS ANALGESIC, ANTI-INFLAMMATORY, ANTICONVULSIVE AND ANTI-PYRETIC ACTION, AND THEIR PREPARATION | ASTA MEDICA AG | 1993-08-31 | — | — | JP | disclosed |
| EP-0539805-A1 | Phthalazines substituted on position 1 by an ether or a thioether group and process for their preparation | ASTA Medica Aktiengesellschaft (DE) | 1993-05-05 | — | — | EP | disclosed |
| US-5037719-A | Image forming method using microcapsules containing silver halide and a salt of a reducing agent | FUJI PHOTO FILM CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| US-4970132-A | CLARITY OF IMAGE; STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1990-11-13 | — | — | US | disclosed |
| US-4902599-A | CONTAINING HYDRAZIDE AND HYDROZINE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219087-A2 | Light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |